Mt. Everest, Nepal – 1993

Spring at the beginning and end and snow at higher altitude made this a memorable trek in the famous Nepalese approach to Everest through Namche, past Ama Dablam, through Pheriche to Gorak Shep (5164m).

Experiments included measurement of changes in intracranial pressure with collaboration with R J Marchbanks at the Royal National Throat, Nose and Ear Hospital, London, the effects of exercise (using Pugh’s bicycle ergometer – see Pugh LGCE et al J Appl Physiol 1964; 19: 431-440), the treatment of mountain sickness with acute acetazolamide, and, in collaboration with Professor Tooke, capillary pressure and permeability changes with studies of albuminuria. The enhanced rate of ascent brought to light an interesting example of march haemoglobinuria in one member of the party.

Publications:

  1. Harvey TC. Om Mani Padme Hum. Lancet 1993; 342(ii): 363.ere JP, Harrison G and BMRES. Alleviation of hypoxia at high altitude; A comparison between oxygen, oxygen and carbon dioxide inhalation and hyperbaric compression. Clinical Science 1990; 79: suppl. 23, 1. DOI: 10.1042/cs079001P 
  2. Bradwell AR. A tough trip to Everest. Queens Medical Magazine 1994; Spring: 21-24.
  3. Bradwell AR. Preventing AMS. Climber and Hillwalker 1994; April: 46.
  4. Wright AD, Winterborn MH, Forster PJG, Delamere J, Harrison GL and Bradwell AR. Carbonic anhydrase inhibition in the immediate therapy of acute mountain sickness. Journal of Wilderness Medicine 1994; 5: 49-55.  
  5. Bradwell AR, Imray C and BMRES. Generalised protein leakage in acute mountain sickness. The 9th International Hypoxia Symposium 1995. Published in: Hypoxia and the Brain. Eds. Sutton, Houston and Coates. 1995; 315: 13. Queen City Printers Inc.
  6. Bradwell AR, Wright AD, Imray C, Fletcher R and BMRES. Progesterone in acute mountain sickness. The 9th International Hypoxia Symposium 1995. Published in: Hypoxia and the Brain. Eds. Sutton, Houston and Coates. 1995; 315: 14. Queen City Printers Inc.
  7. Imray CHE, Cooper M, Mead G, Wright AD, Bradwell AR and Dykes P. Serum phospholipid bound arachidonic acid (22:4) at altitude and in acute mountain sickness. The 9th International Hypoxia Symposium 1995. Published in: Hypoxia and the Brain. Eds. Sutton, Houston and Coates. 1995; 325: 53. Queen City Printers Inc.
  8. Wright AD, Forster PJG, Cadigan PJ, Fletcher RF, Bradwell AR and BMRES. Refinement of Lake Louise self-reporting AMS Questionnaire. The 9th International Hypoxia Symposium 1995. Published in: Hypoxia and the Brain. Eds. Sutton, Houston and Coates. 1995; 343: 123. Queen City Printers Inc.
  9. Wright AD, Imray CHE, Morrissey MSC, Marchbanks RJ and Bradwell AR. Intracranial pressure at high altitude and acute mountain sickness. Clinical Science 1995; 89: 201-204. DOI: 10.1042/cs0890201
  10. Wright AD, Imray CHE, Morrissey MSC, Marchbanks RJ and Bradwell AR. Intracranial pressure at high altitude and acute mountain sickness. Clinical Science 1995; 88(suppl 32); 26p, N91. DOI: 10.1042/cs0890201
  11. Wright AD, Imray CHE, Morrissey MSC, Marchbanks RJ, Bradwell AR and BMRES. Intracranial pressure, high altitude and acute mountain sickness. The 9th International Hypoxia symposium 1995. Published in: Hypoxia and the Brain. Eds. Sutton, Houston and Coates. 1995; 342: 122. Queen City Printers Inc.
  12. Wright AD. Yaks. Aesculapius 1995; (15): 62-63.
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